Homotypic pair formation during conjugation in Tetrahymena thermophila

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DNA synthesis, methylation and degradation during conjugation in Tetrahymena thermophila

We have investigated the timing of DNA synthesis, methylation and degradation during macronuclear development in the ciliate, Tetrahymena thermophila. DNA synthesis was first detected in the anlagen early in macronuclear development, but the majority of DNA synthesis occurred later, after pair separation. Anlagen DNA was first detectably methylated at GATC sites 3-5 hours after its synthesis. O...

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Cytogamy: An Inducible, Alternate Pathway of Conjugation in TETRAHYMENA THERMOPHILA.

We report the occurrence of cytogamy in Tetrahymena thermophila. By analogy to Paramecium, cytogamy generates exconjugant clones that derive their entire genetic information from a single meiotic product of their cytoplasmic parent. Thus, "instant" whole-genome homozygotes are created. Cytogamy has been induced in every strain of T. thermophila tested, and most of the excytogamous progeny have ...

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Multiple introns in a conjugation-specific gene from Tetrahymena thermophila.

Multiple introns have been found in a gene from a ciliated protozoan. This Tetrahymena thermophila gene (cnjB) is large (7.5 kb mRNA) and active only during conjugation, the organism's sexual cycle. Six introns ranging in size from 62 bp to 676 bp were found when we sequenced a 3.1 kb segment of the cnjB gene together with its corresponding cDNA. We estimate, by extrapolation of our current dat...

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SUMOylation is developmentally regulated and required for cell pairing during conjugation in Tetrahymena thermophila.

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ژورنال

عنوان ژورنال: Journal of Cell Science

سال: 1986

ISSN: 1477-9137,0021-9533

DOI: 10.1242/jcs.82.1.223